Researchers identify oestrogen receptor stem cells in the in the mammary gland

(Université libre de Bruxelles) One of the key questions in stem cell and cancer biology is to understand the cellular hierarchy governing tissue development and maintenance and the cancer cell of origin. In a study published in Cell Reports, researchers lead by Cédric Blanpain (Université libre de Bruxelles, Belgium) identified a novel lineage-restricted stem cell in the mammary gland. In the future, this model will be used to assess whether the clinical heterogeneity observed in breast canc...